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Adenovirus
Data on adenovirus discussed by researchers at Federal University of Minas Gerais
September 23rd, 2008
Current study results from the report, 'Epitope mapping and protective immunity elicited by adenovirus expressing the Leishmania amastigote specific A2 antigen: correlation with IFN-gamma and cytolytic activity by CD8+ T cells,' have been published. According to recent research from Brazil, "A2 was identified as an amastigote virulence factor of Leishmania (Leishmania) donovani and as a candidate antigen for vaccine development against visceral leishmaniasis. Here, predicted hydrophilic, class I and II MHC-binding synthetic peptides were used to define epitopes recognized by A2-specific antibodies, CD8+ T and CD4+ T cells, respectively." "Immunization of BALB/c mice...
Source: TB & Outbreaks Week (2008-09-23)
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