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DNA Vaccines
Scientists at Nanjing Medical University detail research in DNA vaccines
September 23rd, 2008
Fresh data on dna are presented in the report 'Recombinant DNA vaccine of the early secreted antigen ESAT-6 by Mycobacterium tuberculosis and Flt3 ligand enhanced the cell-mediated immunity in mice.' According to a study from Nanjing, People's Republic of China, "Cell-mediated immune (CMI) responses are crucial in the protection against tuberculosis. 6-kDa early secretary antigenic target (ESAT-6) is an important T-cell antigen recognized by protective T cells in animal models of infection with Mycobacterium tuberculosis. Flt3 ligand (FL) is a growth factor of dendritic cell (DC), which, as a powerful antigen presenting cell (APC), is essential for CMI response." ...
Source: TB & Outbreaks Week (2008-09-23)
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