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Hantavirus
University of Helsinki, Haartman Institute describes research in hantavirus
September 23rd, 2008
Scientists discuss in 'Oligomerization of hantaviral nucleocapsid protein: charged residues in the N-terminal coiled-coil domain contribute to intermolecular interactions' new findings in hantavirus. According to recent research from Finland, "The nucleocapsid (N) protein of hantaviruses (family Bunyaviridae) is the most abundant component of the virion; it encapsidates genomic RNA segments and participates in viral genome transcription and replication, as well as in virus assembly. During RNA encapsidation, the N protein forms intermediate trimers and then oligomers via 'head-to-head, tail-to-tail' interactions." "In previous work, using Tula hantavirus (TULV) N...
Source: TB & Outbreaks Week (2008-09-23)
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