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TB & Outbreaks Week

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Leishmaniasis Cell Biology



Report summarizes leishmaniasis cell biology study findings from M. Hide and co-researchers



September 23rd, 2008

Data detailed in 'Leishmania infantum: tuning digitonin fractionation for comparative proteomic of the mitochondrial protein content' have been presented. "Leishmania infantum belongs to the Kinetoplastidae that is characterized by a specific mitochondrial DNA, the kinetoplast. This parasite is responsible for both benign cutaneous leishmaniasis and severe visceral leishmaniasis in humans," researchers in Montpellier, France report.

"Molecular determinants of such differences in pathogenesis are not well understood, and the parasites as well as their hosts may contribute to the disease phenotype. Factors that help parasite to adapt its metabolism to nutritional...


Source: TB & Outbreaks Week (2008-09-23)

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