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Mycobacteria
Researchers from Colorado State University describe findings in mycobacteria
September 30th, 2008
"The complete sequence of the Mycobacterium leprae genome, an obligate intracellular pathogen, shows a dramatic reduction of functional genes, with a coding capacity of less than 50%. Despite this massive gene decay, the leprosy bacillus has managed to preserve a minimal gene set, most of it shared with Mycobacterium tuberculosis, allowing its survival in the host with ensuing pathological manifestations," scientists writing in the journal Proteomics report. "Thus, the identification of proteins that are actually expressed in vivo by M. leprae is of high significance in understanding obligate, intracellular mycobacterial pathogenesis. In this study, a...
Source: TB & Outbreaks Week (2008-09-30)
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