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TB & Outbreaks Week

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Tuberculosis



Reports outline tuberculosis study results from Y.J. Jung et al



September 30th, 2008

"Tuberculosis in mice is a lung disease. Airborne infection of this host species with Mycobacterium tuberculosis (Mtb) resulted in 20 days of Mtb growth in the lungs before further growth was inhibited and the level of infection stabilized," investigators in the United States report.

"Inhibition of Mtb growth was associated with the production of interferon-gamma (IFN-gamma)-producing T cells in the lymph nodes and spleen and with the progressive accumulation of these cells in the lungs. Production of IFN-gamma-producing T cells was not discernable until about day 15 of infection, presumably because Mtb did not disseminate from the lungs to the draining lymph nodes and...


Source: TB & Outbreaks Week (2008-09-30)

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