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Clinical Trial Research
New clinical trial research research reported from S. Sundar and co-authors
September 30th, 2008
"Amphotericin B (AB) deoxycholate is highly effective in antimony refractory cases for the treatment of visceral leishmaniasis (VL) in Bihar. But the need for prolonged hospitalisation and frequent, occasionally serious, adverse events are its major drawbacks," scientists writing in the journal Tropical Medicine & International Health report. "Lipid formulations of AB are devoid of these problems, but very expensive. We evaluated the safety and efficacy of a commercial standardised amphotericin B emulsion, a product of AB formulated in lipid emulsion vehicle (ABLE) in the treatment of Indian VL. In this open label, non-comparative study, 15 patients in each group...
Source: TB & Outbreaks Week (2008-09-30)
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