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Life Sciences
Investigators at Johnson & Johnson have published new data on life sciences
October 7th, 2008
According to recent research from Belgium, "The levels of TMC207 (R207910) that can be reached in mouse organs and the sputa of treated patients easily exceed the MIC of the compound and can therefore interfere with in vitro bacterial titrations. We studied the usefulness of protein-enriched media for the prevention of such drug carryover effects." "The average MIC of Mycobacterium tuberculosis was determined on three different media: unsupplemented 7H11 agar (MIC = 0.03 mu g/ml), 7H11 agar supplemented with 5% bovine serum albumin (BSA; MIC = 1 mu g/ml), and LowensteinJensen medium (MIC = 14.33 mu g/ml). In a second stage of the study, the maximal noninhibitory...
Source: TB & Outbreaks Week (2008-10-07)
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