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Tuberculosis
New data from G. Chimote et al illuminate research in tuberculosis
October 7th, 2008
"In this study, the effect of mycobacterial lipids on the surface activity of lung surfactant was evaluated. Mycolic acid and cord factor, the most abundant surface active lipids of the mycobacterial cell wall when combined with Curosurf (TM) led to alteration of its surface properties," scientists in Bombay, India report. "Addition of graded amounts of mycolic acid increased the minimum surface tension of Curosurf (TM) monolayers from <10 mN/m to similar to 20-27 mN/m. Presence of mycolic acid also slowed the rate of Curosurf (TM) adsorption. Similarly, presence of cord factor increased the minimum surface tension achieved by Curosurf (TM) to similar to 16-27 mN/m....
Source: TB & Outbreaks Week (2008-10-07)
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