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TB & Outbreaks Week

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Tuberculosis



Report summarizes tuberculosis study findings from C. Abe and co-researchers



October 7th, 2008

"We reevaluated the BACTEC MGIT 960 antimicrobial susceptibility testing system (MGIT 960 AST) by using 1,112 isolates of Mycobacterium tuberculosis. When the results of MGIT 960 AST were compared with that of the proportion method using Ogawa medium (Ogawa PM), discrepant results were obtained for 30 strains with isoniazid, all resistant by MGIT 960 AST but susceptible by Ogawa PM," scientists in Fukushima, Japan report.

"For 93% of the strains that produced discrepant results, the MIC was 0.4 or 0.8 mu g/ml, showing resistance by the proportion method using Middlebrook agar plates. Furthermore, it was also established by analyses of the katG and inhA genes that...


Source: TB & Outbreaks Week (2008-10-07)

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