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TB & Outbreaks Week

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Tuberculosis



Research conducted at C.B.E. Chee and co-authors has provided new information about tuberculosis



October 7th, 2008

According to recent research published in the Journal of Clinical Microbiology, "There are few head-to-head comparisons of the commercial gamma interferon release assays (GIRAs). We compared the performance of the T-SPOT."

"TB and QuantiFERON-TB Gold In-Tube (QFT-IT) assays in patients with culture-proven pulmonary tuberculosis. Blood was drawn for both assays within 14 days of starting antituberculosis treatment. The QFT-IT indeterminate rate was 3.5%; the T-SPOT. TB failure rate was 1.4%. There was poor agreement between the GIRAs (kappa = 0.257) among the 270 patients with valid results for both tests. The sensitivities of the T-SPOT. TB and QFT-IT assays were...


Source: TB & Outbreaks Week (2008-10-07)

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