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Life Sciences
Researchers at MS Center target life sciences
October 14th, 2008
According to a study from Belo Horizonte, Brazil, "The leishmanicidal activity of four batches of meglumine antimoniate, produced in Farmanguinhos-Fiocruz, Brazil (TAMs), was assessed and compared to Glucantime (R)-Aventis Pharma Ltda. Using the amastigote-like in vitro model, the active concentrations of Sbv varied from 10 mu g/ml to 300 mu g/ml for L. ( L.) chagasi and from 50 mu g/ml to 300 mu g/ml for L. ( L.) amazonensis, with no statistically significant differences among the four batches of TAMs and Glucantime (R)." "The inhibitory concentrations (IC50) determined by the amastigote-infected macrophage model for TAM01/03 and Glucantime (R) were, respectively: 26.3...
Source: TB & Outbreaks Week (2008-10-14)
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