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TB & Outbreaks Week

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Phototherapy



Illinois State University details research in phototherapy



October 14th, 2008

According to a study from the United States, "Dimethyl and diethyl carbaporphyrin ketals inhibit the growth of Leishmania tarentolae promastigotes in vitro."

"The concentration dependency of the inhibitory effect was tested using the MTT assay. The presence of reactive oxygen species, such as singlet oxygen and superoxide, was detected using electron paramagnetic resonance spectroscopy with selected spin traps and confocal microscopy in cultures exposed to these carbaporphyrin ketals," wrote J.B. Morgenthaler and colleagues, Illinois State University.

The researchers concluded: "These unique porphyrinoids show promise as potent inhibitors of...


Source: TB & Outbreaks Week (2008-10-14)

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