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TB & Outbreaks Week

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West Nile Virus



New west nile virus research from McMaster University described



October 14th, 2008

"We examined the West Nile virus (WNV)-specific T cell response in a cohort of 52 patients with symptomatic WNV infections, including neuroinvasive and non-invasive disease. Although all virus proteins were shown to contain T cell epitopes, certain proteins, such as E, were more commonly targeted by the T cell response," investigators in Hamilton, Canada report.

"Most patients exhibited reactivity toward 3-4 individual WNV peptides; however, several patients exhibited reactivity toward >10 individual peptides. The relative hierarchy of T cell reactivities in all patients showed a fixed pattern that was sustained throughout the 12-mo period of the current study....


Source: TB & Outbreaks Week (2008-10-14)

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