Tuberculosis Therapy
Study findings from University of California, Department of Medicine provide new insights into tuberculosis therapy
Published in TB and Outbreaks Week, October 14th, 2008
New research, 'Human macrophage host defense against Mycobacterium tuberculosis,' is the subject of a report. "Tuberculosis has plagued humans for ages, and understanding the host defense mechanisms against this pathogen has been a challenge to immunologists for decades. In mouse models of tuberculosis infection, the role of nitric oxide in antimicrobial activity is well defined," scientists writing in the journal Current Opinion In Immunology report.
"Recent studies indicate a role for the induction of autophagy in host defense against mycobacterial infection. In human macrophages, vitamin D-mediated induction of antimicrobial peptides appears to be an important...
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