TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Life Sciences
Research from University of California yields new data on life sciences
October 21st, 2008
"Exocytosis of lysosomes from macrophages has been described as a response to microbial cytotoxins and haemolysins, as well as for releasing pro-inflammatory cytokines interleukin (IL)-1 beta and IL-18 during inflammasome activation. The mycobacterial ESX-1 secretion system, encoded in part by the Region of Difference-1, is a virulence factor necessary for phagosome escape and host cell lysis by a contact-dependent haemolysin in Mycobacterium marinum," scientists writing in the journal Cellular Microbiology report. "Here we show that ESX-1 from M. marinum and M. tuberculosis is required for Ca2+-dependent induction of lysosome secretion from macrophages....
Source: TB & Outbreaks Week (2008-10-21)
|
