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Necrosis
Researchers from Tufts University discuss findings in necrosis
October 21st, 2008
"Legionella pneumophila enhC(-) mutants were originally identified as being defective for uptake into host cells. In this work, we found that the absence of EnhC resulted in defective intracellular growth when dissemination of intracellular bacteria to neighbouring cells was expected to occur," scientists in the United States report. "No such defect was observed during growth within the amoeba Dictyostelium discoideum. Culture supernatants containing the secreted products of infected macrophages added to host cells restricted the growth of the Delta enhC strain, while tumour necrosis factor alpha (TNF-alpha), at concentrations similar to those found in macrophage...
Source: TB & Outbreaks Week (2008-10-21)
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