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Encephalitis
Data on encephalitis published by researchers at China Medical University
October 21st, 2008
New investigation results, 'Interferon antagonist function of Japanese encephalitis virus NS4A and its interaction with DEAD-box RNA helicase DDX42,' are detailed in a study published in Virus Research. According to recent research from Taichung, Taiwan, "The interferon (IFN) antagonists of Japanese encephalitis virus (JEV) proteins contribute to the JE pathogenesis. Most flavivirus non-structural (NS) proteins correlate with virus-induced inflammation and immune escape." "NS4A proteins of West Nile virus and dengue type 2 virus have been demonstrated to inhibit IFN signaling. In this study, JEV NS4A without the C-terminal 2K domain has been demonstrated to...
Source: TB & Outbreaks Week (2008-10-21)
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