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Leishmaniasis
Findings from T.P.C. Dorlo and co-authors broaden understanding of leishmaniasis
October 28th, 2008
According to recent research from Netherlands, "The pharmacokinetics of miltefosine in leishmaniasis patients are, to a great extent, unknown. We examined and characterized the pharmacokinetics of miltefosine in a group of patients with Old World (Leishmania major) cutaneous leishmaniasis." "Miltefosine plasma concentrations were determined in samples taken during and up to 5 months after the end of treatment from 31 Dutch military personnel who contracted cutaneous leishmaniasis in Afghanistan and were treated with 150 mg miltefosine/day for 28 days. Samples were analyzed with a validated liquid chromatography-tandem mass spectrometry assay with a lower limit of...
Source: TB & Outbreaks Week (2008-10-28)
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