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TB & Outbreaks Week

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Life Sciences



New life sciences study findings recently were published by researchers at University of Freiburg



October 28th, 2008

"Myeloid cell recruitment is a characteristic feature of bacterial meningitis. However, the cellular mechanisms important for the control of Streptococcus pneumoniae infection remain largely undefined," scientists in Freiburg, Germany report.

"Previous pharmacological or genetic studies broadly depleted many myeloid cell types within the meninges, which did not allow defining the function of specific myeloid subsets. Herein we show that besides CD11b(+)Ly-6G(+)CCR2(-) granulocytes, also CD11b(+)Ly-6C(high)CCR2(+) but not Ly-6C(low)CCR2(-) monocytes were recruited in high numbers to the brain as early as 12 h after bacterial challenge. Surprisingly,...


Source: TB & Outbreaks Week (2008-10-28)

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