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Tuberculosis
Research from University of London reveals new findings on tuberculosis
October 28th, 2008
In this recent report, researchers in London, the United Kingdom conducted a study "To determine the effect of oxidative stress on isoniazid-resistant Mycobacterium tuberculosis deficient in catalase/peroxidase activity to varying degrees through mutation in katG. The mutation rate was determined for a set of isogenic strains with different katG alleles giving different catalase and/or peroxidase activities following exposure to the oxidizing agent, hydrogen peroxide." "Mutants were selected on rifampicin, and the location and nature of the mutation were identified by sequencing the rpoB gene. No evidence was found to suggest that strains that had impaired...
Source: TB & Outbreaks Week (2008-10-28)
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