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TB & Outbreaks Week

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Drug Resistance



Scientists at Rockefeller University target drug resistance



October 28th, 2008

According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "Multidrug-resistant strains of Staphylococcus aureus continue to increase in frequency worldwide, both in hospitals and in the community, raising serious problems for the chemotherapy of staphylococcal disease. Ceftobiprole (BPR; BAL9141), the active constituent of the prodrug ceftobiprole medocaril (BAL5788), is a new cephalosporin which was already shown to have powerful activity against a number of bacterial pathogens, including S. aureus."

"In an effort to test possible limits to the antibacterial spectrum and efficacy of BPR, we examined the susceptibilities of the...


Source: TB & Outbreaks Week (2008-10-28)

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