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Aspergillosis
Researchers at University of Exeter release new data on aspergillosis
November 4th, 2008
According to recent research from Exeter, the United Kingdom, "Aspergillus fumigatus is a cosmopolitan saprotrophic fungus that is second only to Candida species as a cause of invasive fungal infections in immunocompromised humans. Current immunodiagnostic tests for invasive aspergillosis (IA) are based on the detection of circulating galactomannan ( GM) in a patient's serum by using a rat monoclonal antibody (MAb), EB-A2, that binds to tetra (1 -> 5)-beta-D-galactofuranoside, the immunodominant epitope in GM." "The potential cross-reactivity of MAb EB-A2 with non-Aspergillus fungi, with contaminating GM in beta-lactam antibiotics and foodstuffs, and with bacterial...
Source: TB & Outbreaks Week (2008-11-04)
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