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Mycobacteria
Studies from X.M. Wang and co-researchers yield new data on mycobacteria
November 11th, 2008
According to a study from Brussels, Belgium, "The acquisition of DNA and the loss of genetic information are two important mechanisms that contribute to strain-specific differences in genome content. In this study, comparative genomics has allowed us to infer the roles of genomic rearrangement and changes in both distribution and copy number of the insertion element, IS1096, in the evolution of Mycobacterium smegmatis mc(2) 155 from its progenitor, M. smegmatis ATCC 607." "Comparative analysis revealed that the ATCC 607 genome contains only 11 IS 1096 elements against the 24 reported in mc(2)155. As mc(2)155 evolved, there was a considerable expansion in the copy number...
Source: TB & Outbreaks Week (2008-11-11)
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