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TB & Outbreaks Week

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Smallpox



Study data from Food & Drug Administration update knowledge of toxicology



November 11th, 2008

According to recent research from the United States, "Brevetoxin uptake and elimination were examined in Eastern oyster (Crassostrea virginica) exposed to recurring blooms of the marine alga Karenia brevis in Sarasota Bay, FL, over a three-year period. Brevetoxins were monitored by in vitro assays (ELISA, cytotoxicity assay, and receptor binding assay) and LC-MS, with in vivo toxicity of shellfish extracts assessed by the traditional mouse bioassay."

"Measurements by all methods reflected well the progression and magnitude of the blooms. Highest levels recorded by mouse bioassay at bloom peak were 157 MU/100 g. Oysters were toxic by Mouse bioassay at levels 20 MU/100 g...


Source: TB & Outbreaks Week (2008-11-11)

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