Tuberculosis
New tuberculosis research from Colorado State University described
Published in TB and Outbreaks Week, November 11th, 2008
According to recent research from the United States, "The hallmark of Mycobacterium tuberculosis infection is the granuloma, a highly dynamic immune structure that contains the bacilli during chronic infection. Here, we examined if alpha 1 beta 1 integrin is required in the development and maintenance of the granulomatous structure during pulmonary infection using the alpha 1 integrin knockout (alpha 1-null) mouse."
"The all 01 integrin is expressed on activated macrophages and T cells, and interacts with collagen molecules in the extracellular matrix (ECM), and thus may play a role in the granulomatous process. Following pulmonary infection with virulent M....
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