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Tuberculosis
New tuberculosis research from Colorado State University described
November 11th, 2008
According to recent research from the United States, "The hallmark of Mycobacterium tuberculosis infection is the granuloma, a highly dynamic immune structure that contains the bacilli during chronic infection. Here, we examined if alpha 1 beta 1 integrin is required in the development and maintenance of the granulomatous structure during pulmonary infection using the alpha 1 integrin knockout (alpha 1-null) mouse." "The all 01 integrin is expressed on activated macrophages and T cells, and interacts with collagen molecules in the extracellular matrix (ECM), and thus may play a role in the granulomatous process. Following pulmonary infection with virulent M....
Source: TB & Outbreaks Week (2008-11-11)
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