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TB & Outbreaks Week

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Tuberculosis



New tuberculosis study findings reported from J.A. Dearaujo and co-authors



November 11th, 2008

"Multi-drug resistant pulmonary tuberculosis (MDR-TB) may result from either insufficiency of the host cellular immune response or mycobacterial. mechanisms of resistance. Mycobacterium tuberculosis-specific CD8(+) and CD4(+) T lymphocytes from MDR-TB patients are poorly studied," scientists writing in the journal Tuberculosis report.

"The aim of this study was to evaluate CD4(+)-IFN-gamma(+), CD4(+)-IL-10(+), CD8(+)IFN-gamma(+) and CD8(+)IL-10(+) cell populations by flow cytometry in non-resistant TB and multi-drug resistant tuberculosis (MDR-TB) patients from mid-central Brazil after stimulation with MPT-51, GlcB and ESAT-6 recombinant antigens from M....


Source: TB & Outbreaks Week (2008-11-11)

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