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Tuberculosis
Research from State University of New York has provided new data on tuberculosis
November 11th, 2008
"Pyrazinamide is unusual among anti-tuberculous agents in its ability to promote a durable cure Pyrazinamide is unusual and shorten the duration of therapy. Yet the basis for this effect is not well understood," scientists writing in the journal Tuberculosis report. "A particularly effective strategy for the development of new drugs can be to synthetically manipulate the well-established structures to improve either the spectrum of activity or some pharmacological. properties. Similar to previously described aminomethylene amides such as morphazinamide, it was found that novel aminomethylene amides can have in vitro activity at higher than the very acidic pH...
Source: TB & Outbreaks Week (2008-11-11)
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