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Cholera
Research findings from S.M.N. Udden et al update understanding of cholera
November 11th, 2008
"The El Tor biotype of Vibrio cholerae O1, causing the current seventh pandemic of cholera, has replaced the classical biotype, which caused the sixth pandemic. The CTX prophages encoding cholera toxin in the two biotypes have distinct repressor (rstR) genes," investigators in Calcutta, India report. "Recently, new variants of El Tor strains that carry the classical type (CTXclass) prophage have emerged. These ''hybrid'' strains apparently originate through lateral gene transfer and recombination events. To explore possible donors of the CTXclass prophage and its mode of transfer, we tested environmental V. cholerae isolates for the presence of CTXclass prophage and...
Source: TB & Outbreaks Week (2008-11-11)
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