Published in TB and Outbreaks Week, November 11th, 2008
"We have previously shown that M. tuberculosis mutants lacking either the trpD or ino1 gene are highly attenuated in mouse models of infection, but can grow when supplemented with tryptophan or inositol, respectively. In this paper we have constructed a double Delta trpD Delta ino1 mutant, and show that this is...
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