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Tuberculosis
Researchers from Monash University describe findings in tuberculosis
November 11th, 2008
New investigation results, 'Crystal structure of a UDP-glucose-specific glycosyltransferase from a Mycobacterium species,' are detailed in a study published in Journal of Biological Chemistry. "Glycosyltransferases (GTs) are a large and ubiquitous family of enzymes that specifically transfer sugar moieties to a range of substrates. Mycobacterium tuberculosis contains a large number of GTs, many of which are implicated in cell wall synthesis, yet the majority of these GTs remain poorly characterized. Here, we report the high resolution crystal structures of an essential GT (MAP2569c) from Mycobacterium avium subsp. paratuberculosis (a close homologue of Rv1208 from...
Source: TB & Outbreaks Week (2008-11-11)
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