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TB & Outbreaks Week

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HIV/AIDS



New HIV/AIDS study findings recently were reported by N. Trudel and co-researchers



November 25th, 2008

According to recent research from Canada, "Visceral leishmaniasis is now recognized as an opportunistic disease in individuals infected with human immunodeficiency virus type 1 (HIV-1). Although the usefulness of HIV-1 protease inhibitors (PIs) in antiretroviral regimens is well documented, little is known about their potential impact in the setting of Leishmania/HIV-1 coinfections."

"We now report that, although selected PIs do not inhibit the growth of Leishmania infantum promastigotes alone in culture, these drugs significantly inhibit the intracellular survival of parasites in phorbol myristate acetate-differentiated THP-1 macrophages and human primary...


Source: TB & Outbreaks Week (2008-11-25)

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