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HIV/AIDS
Research data from G. Bello and colleagues update understanding of HIV/AIDS
November 25th, 2008
Researchers in Brazil conducted a study "To investigate the origin and to reconstruct the onset date of the HIV-1 subtype C epidemic in Brazil. Three independent datasets of subtype C sequences isolated from HIV-1-positive patients from southern Brazil over a period of 15 years (1991-2006) were analyzed: 82 env V3 sequences (213nt), 40 env C2-C5 sequences (559nt), and 72 pol sequences (960nt)." "Brazilian sequences were compared with other subtype C reference strains from the database using basic local alignment search tool, phylogenetic analyses, and searching of specific amino acid signature patterns. Evolutionary parameters were estimated using a Bayesian...
Source: TB & Outbreaks Week (2008-11-25)
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