TB & Outbreaks Week
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Tuberculosis
Research by A.L. Vivan and colleagues in tuberculosis provides new insights
November 25th, 2008
According to recent research from Porto Alegre, Brazil, "Tuberculosis (TB) is one of the most common infectious diseases known to man and responsible for millions of human deaths in the world. The increasing incidence of TB in developing countries, the proliferation of multidrug resistant strains, and the absence of resources for treatment have highlighted the need of developing new drugs against TB." "The shikimate pathway leads to the biosynthesis of chorismate, a precursor of aromatic amino acids. This pathway is absent from mammals and shown to be essential for the survival of Mycobacterium tuberculosis, the causative agent of TB. Accordingly, enzymes of aromatic...
Source: TB & Outbreaks Week (2008-11-25)
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