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TB & Outbreaks Week

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Tuberculosis



Research reports from University of Tennessee provide new insights into tuberculosis



November 25th, 2008

"Nitrofuranylamides (NFAs) are nitroaromatic compounds that have recently been discovered and have potent anti-tuberculosis (TB) activity. A foundational study was performed to evaluate whether this class of agents possesses microbiological properties suitable for future antimycobacterial therapy," scientists in the United States report.

"Five representative compounds of the NFA series were evaluated by standard microbiological assays to determine MICs, MBCs, activity against anaerobic non-replicating persistent Mycobacterium tuberculosis, post-antibiotic effects (PAEs), antibiotic synergy and the basis for resistance. The antimicrobial activity of these compounds was...


Source: TB & Outbreaks Week (2008-11-25)

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