TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Tuberculosis
Studies from University of Illinois have provided new data on tuberculosis
November 25th, 2008
According to recent research from the United States, "We report on a target- based approach to identify possible Mycobacterium tuberculosis DXS inhibitors from the structure of a known transketolase inhibitor." "A small focused library of analogs was assembled in order to begin elucidating some meaningful structure - activity relationships of 3-(4-chloro-phenyl)-5-benzyl4H-pyrazolo[ 1,5-a]pyrimidin-7-one," wrote J.L. Mao and colleagues, University of Illinois. The researchers concluded: "Ultimately we found that 2-methyl-3-(4-fluorophenyl)-5-(4-methoxyphenyl)-4H-pyrazolo[1,5-a]pyrimidin-7-one, although still weak, was able to inhibit M. tuberculosis...
Source: TB & Outbreaks Week (2008-11-25)
|
