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TB & Outbreaks Week

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Tuberculosis



New tuberculosis data have been reported by scientists at University of Buenos Aires



December 2nd, 2008

According to recent research published in the journal Proteins - Structure Function and Bioinformatics, "Mycobacterium tuberculosis is the causative agent of human tuberculosis, one of the most prevalent infectious diseases in the world. Its genome hosts the glbN and glbO genes coding for two proteins, truncated hemoglobin N (trHbN) and truncated hemoglobin O (trHbO), that belong to different groups (I and 11, respectively) of the recently discovered trHb family of hemeproteins."

"The different expression pattern and kinetics rates constants for ligand association and NO oxidation rate suggest different functions for these proteins. Previous experimental and...


Source: TB & Outbreaks Week (2008-12-02)

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