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Researchers from Harvard University discuss findings in life sciences

Published in TB and Outbreaks Week, December 9th, 2008

"Mycobacterium tuberculosis (Mtb) requires an alternative protein secretion system, ESX1, for virulence," scientists writing in the journal Cell Host & Microbe report.

"Recently, Raghavan et al. (2008) reported a new regulatory circuit that may explain how ESX1 activity is controlled during infection," wrote K. Atmakuri and colleagues, Harvard University.

The researchers concluded: "Mtb appears to regulate ESX1 by modulating transcription of associated genes rather than structural components of the secretion system itself."

Atmakuri and colleagues published their study in Cell Host & Microbe (Regulation of protein...

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