TB & Outbreaks Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of TB & Outbreaks Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
West Nile Virus
Recent studies from University of Sydney add new data to west nile virus
December 9th, 2008
According to a study from Sydney, Australia, "In a lethal West Nile virus (WNV) model, central nervous system infection triggered a threefold increase in CD45(int)/CD11b(+)/CD11c(-) microglia at days 6 - 7 postinfection ( p. i.). Few microglia were proliferating, suggesting that the increased numbers were derived from a migratory precursor cell." "Depletion of ''circulating'' (Gr1(-) (Ly6C(lo)) CX3CR1(+)) and ''inflammatory'' (Gr1(hi)/Ly6C(hi)/CCR2(+)) classical monocytes during infection abrogated the increase in microglia. C57BL/6 chimeras reconstituted with cFMS-enhanced green fluorescent protein (EGFP) bone marrow ( BM) showed large numbers of peripherally derived...
Source: TB & Outbreaks Week (2008-12-09)
|
