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Clostridium
Study findings from D.C. Metz et al broaden understanding of clostridium
December 9th, 2008
"Proton pump inhibitors (PPIs) have revolutionized the management of acid-related disorders," investigators in the United States report. "The potential adverse effects related to PPI use fall into four main categories: idiosyncratic reactions, drug-drug interactions, drug-induced reflex hypergastrinemia, and drug-induced hypochlorhydria. Clostridium difficile (C. difficile) colitis, an epidemic of major importance among hospitalized individuals, is potentially facilitated by the fourth mechanism in PPI users. This article interprets the results of the accompanying study by Aseeri et al. that demonstrated a positive association between PPI exposure and C. difficile...
Source: TB & Outbreaks Week (2008-12-09)
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