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Enzyme Research
Studies from M. Thakur et al have provided new data on enzyme research
December 16th, 2008
According to recent research from Chandigarh, India, "Eukaryotic-type serine/threonine protein kinases in bacteria have been implicated in controlling a host of cellular activities. PknA is one of eleven - Such protein kinases from Mycobacterium tuberculosis which regulates morphological changes associated with cell division." "In the present study we provide the evidence for the ability of PknA to transphosphorylate mMurD (mycobacterial UDP-N-acetylmuramoyl-L-alanine:D-glutamateligase), the enzyme involved in peptidoglycan biosynthesis. Its co-expression in Escherichia coli along with PknA resulted in phosphorylation of mMurD. Consistent with these observations,...
Source: TB & Outbreaks Week (2008-12-16)
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