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TB & Outbreaks Week

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Tuberculosis



Reports summarize tuberculosis research from University of Konstanz



December 16th, 2008

According to a study from Constance, Germany, "The evolutionary timing and spread of the Mycobacterium tuberculosis complex (MTBC), one of the most successful groups of bacterial pathogens, remains largely unknown. Here, using mycobacterial tandem repeat sequences as genetic markers, we show that the MTBC consists of two independent clades, one composed exclusively of M. tuberculosis lineages from humans and the other composed of both animal and human isolates."

"The latter also likely derived from a human pathogenic lineage, supporting the hypothesis of an original human host. Using Bayesian statistics and experimental data on the variability of the mycobacterial...


Source: TB & Outbreaks Week (2008-12-16)

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