TB & Outbreaks Week
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Escherichia Coli
Scientists at University of Montreal target Escherichia coli
December 23rd, 2008
"Escherichia coli O157:H7 is an important food-borne pathogen that specifically binds to the follicle-associated epithelium in the intestine, which rapidly brings this bacterial pathogen in contact with underlying human macrophages. Very little information is available about the interaction between E. coli O157:H7 and human macrophages," researchers in Montreal, Canada report. "We evaluated the uptake and survival of strain EDL933 during infection of human macrophages. Surprisingly, EDL933 survived and multiplied in human macrophages at 24 h postinfection. The global gene expression profile of this pathogen during macrophage infection was determined. Inside human...
Source: TB & Outbreaks Week (2008-12-23)
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