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Escherichia Coli
Studies from University of Texas in the area of Escherichia coli described
December 23rd, 2008
According to recent research from the United States, "The expression of the long polar fimbriae (LPF) of enterohemorrhagic Escherichia coli (EHEC) O157:H7 is controlled by a tightly regulated process, and, therefore, the role of these fimbriae during binding to epithelial cells has been difficult to establish. We recently found that histone-like nucleoid-structuring protein (H-NS) binds to the regulatory sequence of the E. coli O157:H7 lpf1 operon and ''silences'' its transcription, while Ler inhibits the action of the H-NS protein and allows lpf1 to be expressed." "In the present study, we determined how the deregulated expression of LPF affects binding of EHEC O157:H7...
Source: TB & Outbreaks Week (2008-12-23)
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