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TB & Outbreaks Week

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Tuberculosis



New tuberculosis findings from H. Ano and co-authors described



December 23rd, 2008

"To determine the prevalence of katGS3 15T mutations in isoniazid (INH) resistant Mycobacterium tuberculosis and to elucidate the association of katGS315T mutations with the prevalence of multidrug-resistant tuberculosis (MDR-TB). From 2001 to 2004, 1655 isolates from all newly registered patients who visited the Osaka Prefectural Medical Centre for Respiratory and Allergic Diseases were tested for drug susceptibility," scientists in Japan report.

"Genotyping was performed using insertion sequence (IS) 61 10-restriction fragment length polymorphism (RHY) in 1629 of 1655 (98.4%) cases. All 145 isolates Of INH-resistant M. tuberculosis, including MDR strains, were tested...


Source: TB & Outbreaks Week (2008-12-23)

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