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TB & Outbreaks Week

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HIV/AIDS Co-Infection



Research reports from University of Cape Town provide new insights into HIV/AIDS co-infection



December 30th, 2008

"Tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) induced by combination antiretroviral therapy (cART) has been attributed to dysregulated expansion of tuberculin IPPD-specific IFN-gamma-secreting CD4(+) T cells. To investigate the role of type I helper T cell expansions and regulatory T cells in HIV-TB IRIS," scientists writing in the American Journal of Respiratory and Critical Care Medicine report.

"Longitudinal and cross-sectional studies of Mycobacterium tuberculosis-specific IFN-gamma enzyme-linked immunospot responses and flow cytometric analysis of blood cells from a total of 129 adults with HIV-1-associated tuberculosis, 98...


Source: TB & Outbreaks Week (2008-12-30)

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