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TB & Outbreaks Week

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Tuberculosis



Studies from Federal University yield new information about tuberculosis



December 30th, 2008

Investigators publish new data in the report 'Role of IFN-gamma +874 T/A single nucleotide polymorphism in the tuberculosis outcome among Brazilians subjects.' According to recent research published in the journal Molecular Biology Reports, "Several genetic cytokine gene variants have been associated with host susceptibility to infectious diseases, including tuberculosis. Based upon the importance of IFN-gamma in protective immunity against Mycobacterium tuberculosis, and the functional role of the IFN-gamma + 874T/A single nucleotide polymorphism in IFN-gamma production, we genotyped 93 Brazilian tuberculosis patients and 266 asymptomatic health care workers, including 150...


Source: TB & Outbreaks Week (2008-12-30)

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