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TB & Outbreaks Week

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Clinical Infectious Diseases



Studies from University of New South Wales yield new data on clinical infectious diseases



December 30th, 2008

According to recent research from Sydney, Australia, "Functional polymorphisms in immune response genes are increasingly recognized as important contributors to the marked individual differences in susceptibility to and outcomes of infectious disease. The acute sickness response is a stereotypical set of illness manifestations mediated by the proinflammatory cytokines induced by many different pathogens."

"The genetic determinants of severity of the acute sickness response have not previously been explored. We examined the impact of functional polymorphisms in cytokine genes with critical roles in the early immune response (tumor necrosis factor-alpha, interleukin-6,...


Source: TB & Outbreaks Week (2008-12-30)

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