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TB & Outbreaks Week

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Clinical Microbiology and Infectious Disease



Recent findings in clinical microbiology and infectious disease described by researchers from University of Berlin



January 6th, 2009

According to recent research published in the European Journal of Clinical Microbiology & Infectious Diseases, "Oral viridans streptococci are a reservoir of resistance genes for pathogens. Through prolonged exposure, long-acting macrolides (e.g., azithromycin) may induce the resistance of the commensals to macrolides more frequently than macrolides with a shorter half-life (e.g., clarithromycin)."

"In a prospective, randomized, evaluator-blinded trial in healthy volunteers receiving standard courses of either azithromycin (n=20) or clarithromycin (n=20), we compared the susceptibility of oral viridans streptococci to macrolides over a period of 12 weeks. There...


Source: TB & Outbreaks Week (2009-01-06)

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