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TB & Outbreaks Week

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Escherichia coli



Findings from University of Manchester, Medical Department advance knowledge in Escherichia coli



January 6th, 2009

According to a study from Manchester, the United Kingdom, "Uropathogenic and invasive Escherichia coli O25:H4-ST131 isolates producing CTX-M-15 extended-spectrum beta-lactamase (ESBL) enzymes have recently been shown to be disseminated across the globe. In the UK, many CTX-M-15 ESBL-producing E. coli strains have been previously defined as belonging to the epidemic strains A-E, as determined by PFGE."

"The present study was carried out to define the relationship between these two groups of pathogenic E. coli. Multilocus sequence typing and PFGE were used for molecular characterization of a collection of 61 ESBL-producing E. coli isolates from across the UK. Strains A to...


Source: TB & Outbreaks Week (2009-01-06)

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